一、个人简介

谭文强，男，博士，副研究员，硕士研究生导师。2018年6月毕业于中国科学院大学，获得海洋化学博士学位。主持中国科学院青促会青年人才项目、山东省自然科学基金、中科院烟台海岸带研究所自主部署课题等项目，作为科研骨干参与了国家重点研发课题、国家自然科学基金、中国科学院科技服务网络计划（STS计划）课题以及企业委托技术开发项目。荣获中国科学院经理特别奖、中国科学院优秀博士学位论文，入选中国科学院青年创新促进会会员。担任Food Chemistry，Food Hydrocolloids，Carbohydrate Polymers等多个期刊审稿人。目前以第一作者及通讯作者在Food Chemistry，Journal of Agricultural and Food Chemistry，Food Hydrocolloids，Carbohydrate Polymers，International Journal of Biological Macromolecules，Materials Science and Engineering: C等国际权威期刊发表SCI论文近30篇；授权国家发明专利近20项，参编专著1部。

二、主要研究项目

1. 中国科学院青年创新促进会人才项目，2020.01至2023.12，主持；

2. 壳聚糖-α-硫辛酸接枝共聚物的设计、合成及其抗氧化活性研究，山东省自然科学基金，2019.07至2022.06，主持；

3. 壳寡糖-多酚抗肿瘤产品的开发，研究所自主部署课题，2020.07至2022.06，主持；

4. 滩涂生物资源循环利用技术与空间功能优化策略，国家重点研发计划课题，2019.11至2022.12，核心科研骨干；

5. 3,6-二氨基甲壳素/壳聚糖的设计、合成及抑真菌活性研究，国家自然科学基金面上项目，2016.01至2019.12，核心科研骨干；

6. 壳寡糖离子化功能基团技术及高质产品开发，中国科学院海洋大科学研究中心重点部署项目，2020.12至2023.11，核心科研骨干。

三、研究方向

主要研究方向为海洋多糖基生物材料，主要针对海洋多糖的功能材料构建，包括病灶微环境响应型智能自组装纳米载药平台、食品活性包装材料、阳离子抑菌材料等，探究其尺寸效应、功能结构域分子多样性对其物化性能和生物活性的影响规律以及在医药、食品、农业、水产等领域的应用。

四、代表性论文

1. Yuting Yuan, Qiuhong Chen, Zhenhua Wang, Yingqi Mi, Fang Dong, Wenqiang Tan*, Zhanyong Guo*. Low molecular weight chitosan based GSH-responsive self-assembled cationic micelle with enhanced anti-tumor effect by combining oxidative damage and chemotherapy. International Journal of Biological Macromolecules, 2024, 268, 131736.

2. Yuting Yuan, Zhenhua Wang, Shengjia Su, Conghao Lin, Yingqi Mi, Wenqiang Tan*, Zhanyong Guo*. Self-assembled low molecular weight chitosan-based cationic micelle for improved water solubility, stability and sustained release of α-tocopherol. Food Chemistry, 2023, 429, 136886.

3. Yuting Yuan, Wenqiang Tan*, Conghao Lin, Jingjing Zhang, Qing Li, Zhanyong Guo*. Development of antioxidant chitosan-based films incorporated with chitooligosaccharide-caffeic acid conjugates. Food Hydrocolloids, 2023, 138, 108431.

4. Yuting Yuan, Zhenhua Wang, Shengjia Su, Yingqi Mi, Qing Li, Fang Dong, Wenqiang Tan*, Zhanyong Guo*. Redox-sensitive self-assembled micelles based on low molecular weight chitosan-lipoic acid conjugates for the delivery of doxorubicin: Effect of substitution degree of lipoic acid. International Journal of Biological Macromolecules, 2023, 247, 125849.

5. Yuting Yuan, Wenqiang Tan*, Jingjing Zhang, Qing Li, Zhanyong Guo*. Water-soluble amino functionalized chitosan: Preparation, characterization, antioxidant and antibacterial activities. International Journal of Biological Macromolecules, 2022, 217, 969–978.

6. Wenqiang Tan, Jingjing Zhang, Xiang Zhao, Qing Li, Fang Dong*, Zhanyong Guo*. Preparation and physicochemical properties of antioxidant chitosan ascorbate/methylcellulose composite films. International Journal of Biological Macromolecules, 2020, 146, 53–61.

7. Wenqiang Tan, Jingjing Zhang, Yingqi Mi, Fang Dong, Qing Li, Zhanyong Guo*. Enhanced antifungal activity of novel cationic chitosan derivative bearing triphenylphosphonium salt via azide-alkyne click reaction. International Journal of Biological Macromolecules, 2020, 165, 1765–1772.

8. Wenqiang Tan, Fang Dong, Jingjing Zhang, Xiang Zhao, Qing Li, Zhanyong Guo*. Physical and antioxidant properties of edible chitosan ascorbate films. Journal of Agricultural and Food Chemistry, 2019, 67, 2530−2539.

9. Wenqiang Tan, Jingjing Zhang, Xiang Zhao, Fang Dong*, Qing Li, Zhanyong Guo*. Synthesis and antioxidant action of chitosan derivatives with amino-containing groups via azide-alkyne click reaction and N-methylation. Carbohydrate Polymers, 2018, 199, 583–592.

10. Wenqiang Tan, Qing Li, Fang Dong, Jingjing Zhang, Fang Luan, Lijie Wei, Yuan Chen, Zhanyong Guo*. Novel cationic chitosan derivative bearing 1,2,3-triazolium and pyridinium: Synthesis, characterization, and antifungal property. Carbohydrate Polymers, 2018, 182, 180–187.

11. Wenqiang Tan, Jingjing Zhang, Yingqi Mi, Fang Dong*, Qing Li, Zhanyong Guo*. Synthesis, characterization, and evaluation of antifungal and antioxidant properties of cationic chitosan derivative via azide-alkyne click reaction. International Journal of Biological Macromolecules, 2018, 120, 318–324.

12. Wenqiang Tan, Qing Li, Fang Dong, Shuai Qiu, Jingjing Zhang, Zhanyong Guo*. Novel 1,2,3-triazoliumfunctionalized starch derivatives: Synthesis, characterization, and evaluation of antifungal property. Carbohydrate Polymers, 2017, 160, 163–171.

13. Wenqiang Tan, Qing Li, Zhenpeng Gao, Shuai Qiu, Fang Dong, Zhanyong Guo*. Design, synthesis of novel starch derivative bearing 1,2,3-triazolium and pyridinium and evaluation of its antifungal activity. Carbohydrate Polymers, 2017, 157, 236–243.

14. Wenqiang Tan, Jingjing Zhang, Fang Luan, Lijie Wei, Yuan Chen, Fang Dong, Qing Li, Zhanyong Guo*. Design, synthesis of novel chitosan derivatives bearing quaternary phosphonium salts and evaluation of antifungal activity. International Journal of Biological Macromolecules, 2017, 102, 704–711.

15. Wenqiang Tan, Jingjing Zhang, Fang Luan, Lijie Wei, Qing Li, Fang Dong, Zhanyong Guo*. Synthesis, characterization, and antifungal evaluation of novel 1,2,3-triazolium-functionalized starch derivative. International Journal of Biological Macromolecules, 2017, 101, 845–851.

16. Wenqiang Tan, Qing Li, Huali Wang, Yan Liu, Jingjing Zhang, Fang Dong, Zhanyong Guo*. Synthesis, characterization, and antibacterial property of novel starch derivatives with 1,2,3-triazole. Carbohydrate Polymers, 2016, 142, 1–7.

17. Wenqiang Tan, Qing Li, Wancong Li, Fang Dong, Zhanyong Guo*. Synthesis and antioxidant property of novel 1,2,3-triazole-linked starch derivatives via ‘click chemistry’. International Journal of Biological Macromolecules, 2016, 82, 404–410.

18. Wenqiang Tan, Qing Li, Fang Dong, Lijie Wei, Zhanyong Guo*. Synthesis, characterization, and antifungal property of chitosan ammonium salts with halogens. International Journal of Biological Macromolecules, 2016, 92, 293–298.

五、代表性专利

1. 含壳寡糖、菊糖、鞣花酸两种或以上的复合物及应用.授权专利号: ZL 201911249528.1.

2. 一种氨基葡萄糖肝素盐及其应用. 授权专利号: ZL 201911242820.0.

3. 一种氨基葡萄糖透明质酸盐及应用. 授权专利号: ZL 201911242790.3.

4. 一种氨基葡萄糖硫酸软骨素盐和制备方法及应用. 授权专利号: ZL 201911241704.7.

5. 一种三氮唑壳聚糖双季铵盐及其制备方法和应用. 授权专利号: ZL 201810600838.2.

6. 一种四丁铵基菊糖氨酯及其制备方法和应用. 授权专利号: ZL 201810275668.5.

7. 一种含壳寡糖的复合物及应用. 授权专利号: ZL 202010777934.1.

8. 一种壳寡糖与姜黄素的复合物及应用. 授权专利号: ZL 201911229225.3.

9. 一种阳离子菊糖烟酸接枝衍生物及其制备方法和应用. 授权专利号: ZL 202210754488.1.

10. 一种羧甲基氨基多糖衍生物及其制备方法和应用. 授权专利号: ZL 201811311525.1.

11. 一种氨基葡萄糖绿原酸盐及其制备方法和应用. 授权专利号: ZL 201810185740.5.

12. 一种壳聚糖绿原酸盐及其制备方法和应用. 授权专利号: ZL 201811093967.3.

六、联系方式

E-mail: wqtan@jou.edu.cn