丁祝进
（2024年3月更新）
一、个人简介
丁祝进，男，1988年12月生，副教授，博士，硕士研究生导师。2017年6月毕业于华中农业大学，获农学博士学位。中国科学院水生生物研究所博士后，丹麦哥本哈根大学访问学者。中国水产学会鱼病专业委员会会员，国际发育与比较免疫学会（ISDCI）会员，江苏省“双创计划” 科技副总，连云港市“花果山英才计划”“双创博士”。
主要从事水产动物免疫与病害防治方向的科研工作，主要研究内容包括病原与宿主互作机制解析、机体抗感染免疫应答机制解析、渔用疫苗、佐剂及免疫增强剂研发等。先后承担江苏省自然科学基金、江苏省农业科技自主创新资金项目、中国博士后科研基金面上项目、江苏省现代农业（紫菜）产业技术体系推广示范基地、连云港市“花果山英才计划”等项目；以第一或通讯作者在Frontiers in Immunology、International Journal of Biological Macromolecules、International Journal of Molecular Sciences、Vaccines、Fish and Shellfish Immunology、Molecular Immunology、Developmental and Comparative Immunology、Journal of Fish Diseases、Aquaculture Reports等期刊发表学术论文30篇，其中以第一或通讯作者发表SCI论文19篇。共指导硕士研究生14名，其中获得研究生国家奖学金3人次。
联系电话：18352807351
E-Mail: dingzhujin@jou.edu.cn
通讯地址：江苏省连云港市苍梧路59号新葡的京集团3512vip海洋科学与水产公司
二、研究方向
水生生物免疫学与病害防治、渔用疫苗及免疫增强剂研发。
三、教育经历
2007.09-2011.06，新葡的京集团3512vip，水产养殖学专业，本科；
2011.09-2017.06，华中农业大学，水产养殖专业，博士。
四、工作经历
2017.06-2019.06，淮海工学院，海洋生命与水产学院，讲师；
2019.06-2020.06，新葡的京集团3512vip，海洋生命与水产学院，讲师；
2020.06-至今，新葡的京集团3512vip，新葡的京集团3512vip，副教授。
五、社会兼职
2022.12-2023.12，兼任SCI期刊Vaccines（IF：7.8）客座编辑（Guest Editor）；
2020.01-至今，兼任Frontiers in Immunology、International Journal of Molecular Sciences、Aquaculture Nutrition、Aquaculture International等SCI期刊审稿人。
六、代表性科研项目
1. “团头鲂内凝集蛋白诱导巨噬细胞极化的机制及其对杀伤作用的影响研究”，江苏省自然科学基金青年基金项目，项目编号：BK20181071，2018-2021；
2. “团头鲂Intelectin介导巨噬细胞通过CXCL8-CXCR1/2途径募集中性粒细胞的机制研究”，中国博士后科学基金面上项目，项目编号：2020M671386，2020-2022；
3. “紫菜育苗中贝壳替代仿生材料的研制与应用”，江苏省农业科技自主创新资金项目，项目编号：CX(20)3110，2020-2023；
4. “江苏现代农业（紫菜）产业技术体系连云港推广示范基地”，江苏省农业农村厅，项目编号：JATS［2022］172，2018年起；
5. “条斑紫菜育苗用基质材料研发”，企业横向项目，项目编号：JOUH23339，2023-2025；
6. “陕西省千河、嘉陵江源、褒河、湑水河浮游生物、底栖动物鉴定、分析”，陕西省动物研究所，项目编号：JOUH23340，2023-2025；
7. “连云港市“花果山英才计划” “双创博士”（创新类）”，连云港市人才办，2018-2020。
七、代表性科研论文
[1] Ting Zhang, Minying Zhang, Zehua Xu, Yang He, Xiaoheng Zhao, Hanliang Cheng, Xiangning Chen, Jianhe Xu, Zhujin Ding*. Screening of protective antigens of Aeromonas hydrophila via reverse vaccinology approach: potential candidates for subunit vaccines development. Vaccines, 2023, 11(7): 1266.
[2] Qijun Wang, Xiaoheng Zhao, Yunlong Liu, Juan Zheng, Hujun Cui, Haotong Wang, Houxu Ding, Hong Liu, Zhujin Ding*. Characterization and expression analysis of genes from Megalobrama amblycephala encoding hemoglobins with extracellular microbicidal activity. Genes (Basel). 2023, 14(10): 1972.
[3] Hujun Cui, Yunlong Liu, Yancui Zheng, Hongping Li, Minying Zhang, Xu Wang, Xiaoheng Zhao, Hanliang Cheng, Jianhe Xu, Xiangning Chen, Zhujin Ding*. Intelectin enhances the phagocytosis of macrophages via CDC42-WASF2-ARPC2 signaling axis in Megalobrama amblycephala. International Journal of Biological Macromolecules, 2023, 236, 124027, doi: 10.1016/j.ijbiomac.2023.124027.
[4] Hongping Li, Yunlong Liu, Yuting Teng, Yancui Zheng, Minying Zhang, Xu Wang, Hanliang Cheng, Jianhe Xu, Xiangning Chen, Xiaoheng Zhao*, Zhujin Ding*. Enhancement of seaweed polysaccharides (fucoidan and laminarin) on the phagocytosis of macrophages via activation of intelectin in blunt snout bream (Megalobrama amblycephala). Frontiers in Marine Science, 2023, 10: 1124880. doi: 10.3389/fmars.2023.1124880.
[5] Minying Zhang, Ting Zhang, Yang He, Hujun Cui, Hong Li, Zehua Xu, Xu Wang, Yunlong Liu, Hongping Li, Xiaoheng Zhao, Hanliang Cheng, Jianhe Xu, Xiangning Chen, Zhujin Ding*. Immunogenicity and protective efficacy of OmpA subunit vaccine against Aeromonas hydrophila infection in Megalobrama amblycephala: An effective alternative to the inactivated vaccine. Frontiers in Immunology, 2023, 14: 1133742. doi: 10.3389/fimmu.2023.1133742.
[6] Xiaoheng Zhao, Xu Wang, Hong Li, Yunlong Liu, Yancui Zheng, Hongping Li, Minying Zhang, Hanliang Cheng, Jianhe Xu, Xiangning Chen, Zhujin Ding*. Comparative expression profiling reveals the regulatory effects of dietary mannan oligosaccharides on the intestinal immune response of juvenile Megalobrama amblycephala against Aeromonas hydrophila infection. International Journal of Molecular Sciences, 2023, 24(3), 2207. doi: 10.3390/ijms24032207.
[7] Hongping Li, Hong Li, Yunlong Liu, Yancui Zheng, Minying Zhang, Xu Wang, Hujun Cui, Haotong Wang, Xiaoheng Zhao, Xiangning Chen, Hanliang Cheng, Jianhe Xu, Zhujin Ding*. Molecular characterization and expression patterns of CXCL8 gene from blunt snout bream (Megalobrama amblycephala) and its chemotactic effects on macrophages and neutrophils. Developmental and Comparative Immunology, 2023, 104658. doi:10.1016/j.dci.2023.104658.
[8] Zhujin Ding*, Xu Wang, Yunlong Liu, Yancui Zheng, Hongping Li, Minying Zhang, Yang He, Hanliang Cheng, Jianhe Xu, Xiangning Chen, Xiaoheng Zhao*. Dietary mannan oligosaccharides enhance the nonspecific immunity, intestinal health, and resistance capacity of juvenile blunt snout bream (Megalobrama amblycephala) against Aeromonas hydrophila. Frontiers in Immunology, 2022, 13: 863657.
[9] Hujun Cui, Hong Li, Minying Zhang, Hongping Li, Xu Wang, Zirui Wang, Wei Zhai, Xiangning Chen, Hanliang Cheng, Jianhe Xu, Xiaoheng Zhao, Zhujin Ding*. Molecular characterization, expression, evolutionary selection, and biological activity analysis of CD68 gene from Megalobrama amblycephala. International Journal of Molecular Sciences, 2022, 23(21), 13133.
[10] Hujun Cui, Xiaoxue Shen, Yancui Zheng, Peng Guo, Zhaotian Gu, Yanan Gao, Xiaoheng Zhao, Hanliang Cheng, Jianhe Xu, Xiangning Chen, Zhujin Ding*. Identification, expression patterns, evolutionary characteristics and recombinant protein activities analysis of CD209 gene from Megalobrama amblycephala. Fish and Shellfish Immunology, 2022, 126: 47-56.
[11] Yunlong Liu, Yuan Yan, Zhen Han, Yancui Zheng, Xu Wang, Minying Zhang, Hongping Li, Jianhe Xu, Xiangning Chen, Zhujin Ding*, Hanliang Cheng*. Comparative effects of dietary soybean oil and fish oil on the growth performance, fatty acid composition and lipid metabolic signaling of grass carp, Ctenopharyngodon idella. Aquaculture Reports, 2022, 22: 101002.
[12] Yang He1, Zhujin Ding1, Marana Moonika, Dalsgaard Inger, Rzgar Jaafar, Heidi Mathiessen, Asma Karami, Per Kania, Kurt Buchmann*. Immersion vaccines against Yersinia ruckeri infection in rainbow trout: Comparative effects of strain differences. Journal of Fish Diseases, 2021, 44: 1937-1950.
[13] Yancui Zheng, Yunlong Liu, Hongping Li, Xu Wang, Minying Zhang, Xin Shen, Hanliang Cheng, Jianhe Xu, Xingqiang Wang, Hong Liu, Zhujin Ding*, Xiaoheng Zhao*. Novel insights into the immune regulatory effects of Megalobrama amblycephala intelectin on the phagocytosis and killing activity of macrophages. Molecular immunology, 2021, 137: 145-154.
[14] Zhujin Ding, Xiaoheng Zhao, Jixiu Wang, Feng Zhang, Weimin Wang, Hong Liu*, Intelectin mediated phagocytosis and killing activity of macrophages in blunt snout bream (Megalobrama amblycephala). Fish and Shellfish Immunology, 2019, 87: 129-135.
[15] Zhujin Ding, Xiaoheng Zhao, Lei Cui, Qianhui Sun, Feng Zhang, Jixiu Wang, Weimin Wang, Hong Liu*, Novel insights into the immune regulatory effects of ferritins from blunt snout bream, Megalobrama amblycephala. Fish and Shellfish Immunology, 2019, 87: 679-687.
[16] Zhujin Ding, Xiaoheng Zhao, Qifeng Zhan, Lei Cui, Qianhui Sun, Li Lin, Weimin Wang, Hong Liu*, Characterization and expression analysis of an intelectin gene from Megalobrama amblycephala with strong response to bacterial infection and excellent bacterial binding and agglutination activity. Fish and Shellfish Immunology, 2017, 61: 100-110.
[17] Zhujin Ding, Xiaoheng Zhao, Qifeng Zhan, Lei Cui, Qianhui Sun, Weimin Wang, Hong Liu*, Comparative analysis of two ferritin subunits from blunt snout bream (Megalobrama amblycephala): characterization, expression, iron depriving and bacteriostatic activity. Fish and Shellfish Immunology, 2017, 66: 411-422.
[18] Zhujin Ding, Xiaoheng Zhao, Lina Su, Fengjuan Zhou, Nan Chen, Junjie Wu, Xiaoqin Fu, Fan Wu, Weimin Wang, Hong Liu*, The Megalobrama amblycephala transferrin and transferrin receptor genes: molecular cloning, characterization and expression during early development and after Aeromonas hydrophila infection. Developmental and Comparative Immunology, 2015, 49(2): 290-297.
[19] Zhujin Ding, Junjie Wu, Lina Su, Fengjuan Zhou, Xiaoheng Zhao, Wei Deng, Jie Zhang, Shikai Liu, Weimin Wang, Hong Liu*, Expression of heat shock protein 90 genes during early development and infection in Megalobrama amblycephala and evidence for adaptive evolution in teleost. Developmental and Comparative Immunology, 2013, 41: 683-693.
[20] 丁祝进，崔虎军，谷昭天. 鱼类趋化因子家族的研究进展. 中国水产科学，2021，28(9): 1227-1237.
[21] 丁祝进，崔虎军，谷昭天，赵晓恒，程汉良. 鱼类巨噬细胞标记物的研究进展. 水产科学，2023，1-14. https://doi.org/10.16378/j.cnki.1003-1111.21145.
八、代表性专利
1. 一种装配式贝壳固定板、其制备方法和应用，授权号：ZL202011172481.6；
2. 一种装配式紫菜育苗基板及其使用方法，授权号：ZL202011172523.6；
3. 团头鲂转铁蛋白基因SNP分子标记及其应用，授权号：ZL201610590362.X；
4. 一种团头鲂转铁蛋白受体基因SNP分子标记及其应用，授权号：ZL201610785387.5。
